KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS39
All Species:
39.09
Human Site:
Y727
Identified Species:
71.67
UniProt:
Q96JC1
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96JC1
NP_056104.2
886
101809
Y727
E
E
Y
C
H
K
H
Y
D
R
N
K
D
G
N
Chimpanzee
Pan troglodytes
XP_510331
886
101752
Y727
E
E
Y
C
H
K
H
Y
D
Q
N
K
D
G
N
Rhesus Macaque
Macaca mulatta
XP_001102792
886
101693
Y727
E
E
Y
C
H
K
H
Y
D
Q
N
K
D
G
N
Dog
Lupus familis
XP_849407
886
101720
Y727
E
E
Y
C
H
K
H
Y
D
Q
N
R
D
G
N
Cat
Felis silvestris
Mouse
Mus musculus
Q8R5L3
886
101674
Y727
K
E
Y
C
H
K
H
Y
D
Q
N
K
E
G
N
Rat
Rattus norvegicus
XP_001075756
886
101629
Y727
K
E
Y
C
H
K
H
Y
D
Q
N
K
E
G
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518189
1309
145152
Y1150
E
R
Y
C
Q
K
H
Y
D
Q
N
R
D
G
S
Chicken
Gallus gallus
NP_001026365
875
100503
Y716
E
N
Y
C
H
K
H
Y
D
R
N
K
D
G
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A4IG72
863
97029
S705
E
E
Y
C
S
W
A
S
A
S
Q
D
S
S
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650702
876
100146
Y718
T
A
Y
A
E
A
H
Y
K
E
D
K
H
I
F
Honey Bee
Apis mellifera
XP_392710
866
100055
Y712
I
E
Y
C
N
K
V
Y
T
R
Y
Q
K
N
A
Nematode Worm
Caenorhab. elegans
NP_001041163
923
104932
Y742
E
E
Y
C
R
L
Y
Y
N
A
H
D
E
T
N
Sea Urchin
Strong. purpuratus
XP_798217
824
94304
D708
V
Y
A
H
I
L
K
D
T
R
Q
A
E
E
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.3
98
N.A.
97.4
96.8
N.A.
59.2
92.7
N.A.
26.4
N.A.
35.4
42.4
31.7
51.5
Protein Similarity:
100
99.8
99.7
99.3
N.A.
98.9
98.5
N.A.
62.8
96.1
N.A.
46.8
N.A.
55.6
62
52.5
68.4
P-Site Identity:
100
93.3
93.3
86.6
N.A.
80
80
N.A.
66.6
93.3
N.A.
26.6
N.A.
26.6
40
40
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
86.6
93.3
N.A.
26.6
N.A.
33.3
53.3
66.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
8
0
8
8
0
8
8
0
8
0
0
8
% A
% Cys:
0
0
0
85
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
8
62
0
8
16
47
0
0
% D
% Glu:
62
70
0
0
8
0
0
0
0
8
0
0
31
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
62
0
% G
% His:
0
0
0
8
54
0
70
0
0
0
8
0
8
0
0
% H
% Ile:
8
0
0
0
8
0
0
0
0
0
0
0
0
8
0
% I
% Lys:
16
0
0
0
0
70
8
0
8
0
0
54
8
0
0
% K
% Leu:
0
0
0
0
0
16
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
8
0
0
0
8
0
62
0
0
8
62
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
8
0
0
0
0
47
16
8
0
0
0
% Q
% Arg:
0
8
0
0
8
0
0
0
0
31
0
16
0
0
0
% R
% Ser:
0
0
0
0
8
0
0
8
0
8
0
0
8
8
8
% S
% Thr:
8
0
0
0
0
0
0
0
16
0
0
0
0
8
0
% T
% Val:
8
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
93
0
0
0
8
85
0
0
8
0
0
0
16
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _